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Phelix Research & Development

This website provides an overview of Phelix's ground-breaking work in the support of research and development of diagnostic tests, and ultimately, treatments of antibiotic resistant chronic infectious diseases through the use of bacteriophages. We want to draw both the expert and the non-scientist's attention.

This website provides an overview of Phelix's ground-breaking work in the support of research and development of diagnostic tests, and ultimately, treatments of antibiotic resistant chronic infectious diseases through the use of bacteriophages. It is intended for both the expert and the non-scientist.

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Bacteriophages Research

We believe bacteriophage research to be an area of extreme importance, with great potential still to be explored and exploited in the development of new treatment for infectious disease.

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Phage-based test

Phelix is working on a new rapid and highly sensitive phage based diagnostic method, testing blood and/or urine samples to detect Borrelia spp.

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Alternative to antibiotics

Could bacteriophages provide an alternative to antibiotics, providing a solution to the problem of increasing antibiotic resistance, one of the largest threats to global health?

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“Claude Bernard was right. The pathogen is nothing. The terrain is everything.” Louis Pasteur (1822-1895)

‘’ Every noble work is at first impossible.’’ Thomas Carlyle (1785-1881)

Phelix goals

Phelix studies chronic infections and bacteriophages. Our first development will allow a diagnostic method, prevention methods and innovative treatments for Lyme disease. Our goal is to apply this knowledge to fight infectious diseases suspected of being responsible for the most common neurodegenerative diseases.

Background

With the expansive knowledge from the entire global community of scientists available to us in the form of research papers, we are able to identify current issues in the related field and draw links between particular problems to consider new models of infectious disease.

Research

Currently, we are focussed on supporting research surrounding bacteriophages and their potential uses in chronic infection.
However, we are constantly looking for new ways to understand neurodegenerative diseases.

Development

We are working on developing a new diagnostic method to test for Borrelia spp. in those suspected of carrying the bacteria.
It is a bacteriophage-based test of the patient’s blood or urine, which has improved sensitivity and specificity.

We need you

Phelix relies entirely on donations to fund a range of research projects on Lyme disease, its diagnosis and its treatment by specific bacteriophages. This research and these same strategies will also serve another great cause: the identification of infections involved in the onset and morbidity of serious neurodegenerative diseases, particularly autism spectrum disorders. 100% of your donations go to research, as our team is made up of volunteers.

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Our Ambitions

About neurodegenerative conditions

More and more clinical and medical evidence indicates that many neurodegenerative diseases (Autism Spectrum Disorder and Alzheimer’s Disease, most relevantly) have infectious origins. The development of a more sensitive and specific diagnostic test would be a game changer in the way we diagnose, treat and prevent these conditions.

About bacteriophages

As antibiotic resistance increases and the number of new antibiotics being brought to the market decreases, the use of bacteriophages as an alternative to antibiotics and a novel therapeutic for infectious disease, either through the use of lytic phages or phage-encoded enzymes, seems increasingly attractive.

About chronic infections

Currently, there is no standardised method of investigation into infectious disease in chronic conditions. We aim to generalise our phage-based test to other pathogens to investigate the epigenetic implication of infection in chronic conditions.