Phelix was born in 2014, discover the story of the organization:
Phelix roadmap
2018
Chicago ILADS 2018
Louis Teulieres will be presenting
2017
Investigate the use of phages and phage-encoded enzymes as novel therapeutics
Isolate and characterise lytic and temperate Borrelia phages
Present and Future Research in the UK workshop, Edinburgh
Dr Jinyu Shan, invited speaker for Lyme and other tick borne diseases, Edinburgh, 1 June 2017.
‘Enquete de Sante’ 30th of may 2017, France 5, TV program on Lyme Disease
Dr. Louis Teulières invited as Panel Member of the TV program
JID’IMVT, Strasbourg, 8 June 2014
Dr. Louis Teulières conference at Journées Internationales D’Information sur les Maladie Vectorielles à Tiques (JID’IMVT)
IV International Conference on Antimicrobial Research (ICAR), 29 June -1 July 2016, Malaga, Spain
Dr. Jinyu Shan Invited speaker
15th Lyme Disease Action Conference, September 17, 2016, Cambridge, UK
Dr. Jinyu Shan Invited Speaker
ILADS European Conference, Paris May 2017: Development of Bacteriophages Targeted Against Borrelia
Dr. Louis Teulières Invited Speaker and Dr. Jinyu Shan Poster Presenter at International Lyme and Associated Disease Society (ILADS) 7th European Conference, Paris, 19-20 May 2017. Interview of Dr. Teulières : https://www.youtube.com/watch?v=__siEPKk1qo
First round of validation of phage-based Lyme diagnostics was completed against 222 patient serum samples
This was a preliminary work for a clinical trial to compare the specificity and sensitivity of our phage-based test vs. ELISA, Western Blot (IgG, IgM) and PCR 16S
Mastering of the enzymatic-protein production with lytic properties
Dr Jinyu Shan visited Professor Shengce Tao at Shanghai Jiaotong University to established the pipeline for lab manufacturing two Borrelia phage enzymes, holin and endolysin
Both enzymes are predicted to have ‘anti-Borrelia’ activity
Presentation at University Hospital Raymond Poincarré Garches
Exhibition of the preliminary data and concept of the calibration study
New phage-based test improvement with very high sensitivity and specificity
2016
Phage-based Lyme diagnostics was optimised and validated in lab against lab Borrelia cultures
ILADS 17th Annual Scientific Conference, Philadelphia, PA, 4-6 November 2016
Dr. Jinyu Shan Invited Speaker and Dr. Louis Teulières Panel Member of International Lyme and Associated Disease Society (ILADS)
First calibration protocol for the phage-based test
AONM Conference, London October 2016: Neuroborreliosis, Chronic Lyme Disease
Dr. Louis Teulières Invited Speaker
Design of new Phage-based Lyme diagnostics (Borrelia spp.)
ILADS 6th European Conference, 10 – 11 June 2016, Helsinki, Finland
Dr. Jinyu Shan Poster Presentation at International Lyme and associated diseases society (ILADS)
University of Leicester awards £35 000 to Phelix for innovation work on Borrelia phage
Finished the optimization of Borrelia spp. culturing & temperature sensitivity tests in the lab
Setting up of the tick collection network across the UK
Euroscicon phage London meeting, January 2016, London, UK
Dr. Jinyu Shan Poster Presentation on 19-21 January and conference on phages on 27-29 January
2015
Development of the bacteria based and phage based PCR technique for detecting Borrelia spp.
Oxford Bacteriophage Conference – Phages 2015, 1-2 September 2015, Cambridge, UK
Dr. Jinyu Shan oral presentation on “Phage in medicine, food and biotechnology”
14th International Conference on Lyme Borreliosis and other Tick-borne Diseases, 27-30 September 2015, Vienna, Austria
Dr. Jinyu Shan Poster Presentation
First scientific contact with veterinary authorities and breeders, in order to study animal reservoirs and phages prevalence
Retour sur la présence de France Lyme et du Dr Louis Teulières lors de l’AG annuelle de l’APCLD le 12 juin 2015.
Tick collection started & dissection technique mastered
Dr. Ying Jia joins the research team
Prophage induction of Borrelia spp.
Dr. Jinyu Shan joins the research team
2014
Professor Martha Clockie masters the correct technique to grow Borrelia spp. in a lab
Collaboration signed between Leicester University and Phelix
Creation of Phelix Research & Development and Phelix France
Dr. Louis Teulières on TF1 French Channel
Watch the replay from 15 minutes 20 seconds: http://www.lci.fr/france/le-20-heures-du-7-fevrier-2014-1125239.html
2013
Dr. Louis Teulières, François-Xavier Louvet, Pr. Martha Clockie & Pr. Christian Perronne initiate the idea of collaboration
Dr. Louis Teulières has the idea to study Borrelia spp. phages
François-Xavier Louvet & Dr. Louis Teulières begin their collaboration
2012
Conference on autism, 15 November 2012, Paris
Dr. Louis Teulières conference on “Autisme et troubles envahissants du développement, des solutions pour aujourd’hui” http://francelyme.fr/conference-sur-lautisme-15-novembre-2012-paris/
Dr. Phlippe Bottero meets François-Xavier Louvet and introduces the concept of chronic infection
TV program on autism origins, FR3 French channel
Link: https://www.youtube.com/watch?v=QUsfxYZsEOs